Yazar "Mahiroğulları, Mahir" için listeleme
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Anterior glenohumeral instability: Classification of pathologies of anteroinferior labroligamentous structures using MR arthrography
Mutlu, Serhat; Mahiroğulları, Mahir; Güler, Olcay; Uçar, Bekir Yavuz; Mutlu, Harun; Sönmez, Güner; Mutlu, Hakan (Hindawi, 2013)We examined labroligamentous structures in unstable anteroinferior glenohumeral joints using MR arthrography (MRA) to demonstrate that not all instabilities are Bankart lesions. We aimed to show that other surgical protocols ... -
Are biological agents toxic to human chondrocytes and osteocytes?
İşyar, Mehmet; Bilir, Bülent; Yılmaz, İbrahim; Çakmak, Selami; Yaşar Şirin, Duygu; Yıldırım Güzelant, Aliye; Mahiroğulları, Mahir (BioMed Central, 2015)Purpose: The aim of the present study is to investigate the effects of biological agents (BAs) on human chondrocytes and osteocytes in vitro. Methods: Primary cell cultures obtained from gonarthrosis patients were divided ... -
Are chondrocytes damaged when rheumatologic inflammation is suppressed?
Yıldırım Güzelant, Aliye; İşyar, Mehmet; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Çakmak, Selami; Mahiroğulları, Mahir (Taylor & Francis Inc, 2017)Aim: The use of biological agents (BAs) for treating diseases such as rheumatoid arthritis (RA), spondyloarthropathy, and systemic lupus erythematosus to reduce inflammation has been fruitful. Especially as part of the ... -
Are the leading drugs against Staphylococcus aureus really toxic to cartilage?
Doğan, Mustafa; İşyar, Mehmet; Yılmaz, İbrahim; Bilir, Bülent; Şirin, Duygu Y.; Çakmak, Selami; Mahiroğulları, Mahir (Elsevier Ltd, 2016)Many studies have shown that the toxic effects of local antibiotics on bone and cartilage limit orthopedic surgeons. In this study, we evaluated three antibacterial agents used locally to treat highly mortal and morbid ... -
Are we economically efficient enough to ıncrease the potential of in vitro proliferation of osteoblasts by means of pharmacochemical agents?
İşyar, Mehmet; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Tosun, Hacı Bayram; Mahiroğulları, Mahir (Bentham Open, 2016)Background: The aim of this study was to test the necessity of using expensive and unaccesible pharmacological-chemical agents in the proliferation of bone tissue cultures and in the induction of mineralized matrix formation ... -
Are we using slow-acting symptomatic chondroprotective drugs conscious enough?
Gümüştaş, Seyit Ali; Öznam, Kadir; Mutlu, Çağrı Ata; Kaya, Yasin Emre; Yılmaz, İbrahim; İşyar, Mehmet; Yıldırım Güzelant, Aliye; Güler, Olcay; Akkaya, Semih; Mahiroğulları, Mahir (Bentham Open, 2017)Background: Osteochondral injuries constitute an entity that is widespread and can be seen in patients of all ages. Actual treatment modalities aim to relieve pain, obtain full range of movement of the joint, and improve ... -
Assessing the negative impact of phenyl alkanoic acid derivative, a frequently prescribed drug for the suppression of pain and inflammation, on the differentiation and proliferation of chondrocytes
Gümüştaş, Seyit Ali; Yılmaz, İbrahim; İşyar, Mehmet; Şirin Yaşar, Duygu; Batmaz, Ahmet Güray; Uğraş, Ali Akın; Öznam, Kadir; Çiftçi, Zafer; Mahiroğulları, Mahir (BMC, 2016)Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are frequently prescribed to relieve pain and inflammation. These NSAIDs have also analgesic effects and can be administered via oral, injectable, and topical ... -
The association between different molecular weights of hyaluronic acid and CHAD, HIF-1 alpha, COL2A1 expression in chondrocyte cultures
Yaşar Şirin, Duygu; Kaplan, Necati; Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi; Akyuva, Yener; Kaya, Yasin Emre; Öznam, Kadir; Akkaya, Nuray; Güler, Olcay; Akkaya, Semih; Mahiroğulları, Mahir (Spandidos Publications Ltd, 2018)The aim of the present study was to investigate the effects of three different formulations of hyaluronic acid (HA): Low molecular weight (MW) Sinovial One((R)), medium MW Viscoplus((R)) and high MW Durolane((R)), on ... -
Bilateral low-energy sequential femoral shaft fractures in patients on long-term bisphosphonate therapy
Çakmak, Selami; Mahiroğulları, Mahir; Keklikçi, Kenan; Sarı, Enes; Erdik, Baran; Rodop, Osman (2013)The aim of this study was to evaluate the demographic characteristics of patients with bilateral bisphosphonate-related low-energy femoral shaft fractures. Methods: The clinical registry was reviewed for patients with ... -
Can a biodegradable implanted bilayered drug delivery system loaded with BMP-2/BMP-12 take an effective role in the biological repair process of bone-tendon injuries? A preliminary report
Kömür, Baran; Akyuva, Yener; Karaslan, Numan; İşyar, Mehmet; Gümüştaş, Seyit Ali; Yılmaz, İbrahim; Akkaya, Semih; Şirin, Duygu Yaşar; Mutlu, Çağri Ata; Batmaz, Ahmet Güray; Güler, Olcay; Mahiroğulları, Mahir (Hindawi Ltd, 2017)Background. Use of biodegradable and biocompatible materials in the orthopedic surgery is gaining popularity. In this research, the rate of controlled release of a bilayered prototype biomaterial designed to promote ... -
Can prosthesis design of total knee arthroplasty affect balance?
İşyar, Mehmet; Saral, İlknur; Güler, Olcay; Çakar, Engin; Mahiroğulları, Mahir (Turkish Joint Diseases Foundation, 2015)Objectives: In this study, we aimed to investigate whether posterior cruciate ligament (PCL) retaining or substituting in total knee arthroplasty affect the balance. Patients and methods: Between March 2010 and April 2014, ... -
Chondrocyte proliferation, viability and differentiation is declined following administration of methylphenidate utilized for the treatment of attention-deficit/hyperactivity disorder
Gümüştaş, Funda; Yılmaz, İbrahim; Yaşar Şirin, Duygu; Gümüştaş, Seyit Ali; Batmaz, Ahmet Güray; İşyar, Mehmet; Akkaya, Şeyda; Mahiroğulları, Mahir (Sage Publications Ltd, 2017)Purpose: Methylphenidate (MPH) derivative drugs are used because of psychostimulants effects on attention-deficit hyperactivity disorder in children and adults. As far as we know, toxic or anti-proliferative effects of MPH ... -
Comparison of extracorporeal shock wave therapy in acute and chronic lateral epicondylitis
Köksal, İsmet; Güler, Olcay; Mahiroğulları, Mahir; Mutlu, Serhat; Çakmak, Selami; Akşahin, Ertuĝrul (Turkish Association of Orthopaedics and Traumatology, 2015)Objective: The aim of this study is to evaluate and compare the results of extracorporeal shock wave therapy (ESWT) in the treatment of acute (<3 months) lateral epicondylitis (LE) and chronic (>6 months) LE groups. Methods: ... -
Comparison of four different reduction methods for anterior dislocation of the shoulder
Güler, Olcay; Ekinci, Şafak; Akyıldız, Faruk; Tirmik, Üzeyir; Çakmak, Selami; Uǧraş, Ali Akın; Pişkin, Ahmet; Mahiroğulları, Mahir (BioMed Central, 2015)Background: Shoulder dislocations account for almost 50 % of all major joint dislocations and are mainly anterior. Objective: The aim is a comparative retrospective study of different reduction maneuvers without anesthesia ... -
A comparison of isokinetic muscle strength in patients with chondromalacia patella: A cross-sectional study
Saral, I.; Ağırman, Mehmet; Basat, H.; Surucu, Serkan; Mahiroğulları, Mahir; Çakar, Engin (Verduci Editore s.r.l, 2022)– OBJECTIVE: Chondromalacia patella (CMP), which is one of the most common causes of anterior knee pain in young adults, is often accompanied by reflex inhibition of the quadriceps muscle. In this respect, a significant ... -
Comparison of mortality rates and functional results after transtibial and transfemoral amputations due to diabetes in elderly patients-a retrospective study
Şeker, Ali; Kara, Adnan; Çamur, Savaş; Malkoç, Melih; Sönmez, Mehmet Mesut; Mahiroğulları, Mahir (Elsevier Science Bv, 2016)Introduction: This study aimed to compare mortality rates and functional results of transtibial and transfemoral amputations in elderly patients with diabetes. Methods: 87 amputees [54 (62.1%) transtibial and 33 (37.9%) ... -
Comparison of MRI results of grafts obtained by unilateral anterior cruciate ligament reconstruction either using anteromedial portal only or transtibial method with contralateral healthy knee: Tibial tunnel or graft insertion?
Güler, Olcay; Mahiroğulları, Mahir; Mutlu, Serhat; Çerçi, Mehmet Halis; Şeker, Ali; Çakmak, Selami (SAGE Publications Ltd, 2014)Objectives: Our aim is to compare graft angles and tibial tunnel insertion in patients undergone single bundle ligament reconstruction using anatomical anteromedial (AM) and transtibial (TT) method with the contralateral ... -
Comparison of quadriceps muscle volume after unilateral total knee arthroplasty with and without tourniquet use
Güler, Olcay; Mahiroğulları, Mahir; İşyar, Mehmet; Pişkin, Ahmet; Yalçın, Sercan; Mutlu, Serhat; Şahin, Bünyamin (Springer, 2016)Determination of the effect of tourniquet use in total knee arthroplasty (TKA) on thigh and quadriceps muscle volume using magnetic resonance imaging (MRI). A total of 148 knees of 74 patients (mean age 66.5 +/- 4.8 years; ... -
Comparison of screw fixation with elastic fixation methods in the treatment of syndesmosis injuries in ankle fractures
Seyhan, Mustafa; Dönmez, Ferdi; Mahiroğulları, Mahir; Çakmak, Selami; Mutlu, Serhat; Güler, Olcay (Elsevier, 2015)17 patients with ankle syndesmosic injury were treated with a 4.5 mm single cortical screw fixation (passage of screw 4 cortices) and 15 patients were treated with single-level elastic fixation material. All patients were ... -
Comparison of short-term results of intraarticular platelet-rich plasma (PRP) and hyaluronic acid treatments in early-stage gonarthrosis patients
Güler, Olcay; Mutlu, Serhat; İşyar, Mehmet; Şeker, Ali; Kayaalp, Mahmut Enes; Mahiroğulları, Mahir (Springer-Verlag, 2015)The present study aimed to compare short-term clinical outcomes between intraarticular platelet-rich plasma (PRP) and hyaluronic acid (HA) treatments in early-stage gonarthrosis patients. Data of gonarthrosis patients, who ...